#Genomics

3 posts tagged with "Genomics"

A Bioinformatician's Guide to Choosing Genomic Foundation Models

2026-01-19T10:30:00Z•21 min read

#foundation models #genomics #bioinformatics #deep learning #protein language models #dna models #esm-2 #dnabert-2 #hyenadna #scgpt

A practical guide to selecting genomic foundation models for bioinformatics tasks. Covers ESM-2, DNABERT-2, HyenaDNA, Nucleotide Transformer, scGPT, and Evo with specific recommendations for DNA sequence analysis, protein structure prediction, and single-cell analysis based on hardware requirements, inference speed, and task type.

When the Algorithm Can't Explain Itself: ML Interpretability in Precision Oncology

2026-01-03T10:00:00Z•19 min read

#machine learning #precision oncology #explainability #genomics #graph neural networks #clinical ai

Machine learning models now outperform FDA-approved biomarkers in predicting treatment response, but the best-performing models often resist explanation. Here's how precision oncology is navigating the trade-off between performance and interpretability.

Why Two Gene Discovery Methods Found Completely Different Genes (And Why That Matters for Your Health)

2025-11-06T10:00:00+00:00•14 min read

#genomics #gwas #bioinformatics #drug-discovery #statistical-genetics

How gene length, trait specificity, and luck systematically distort which genes we think are important for disease, and what researchers should do about it