MIMIC: One 1B Model Across the Central Dogma, and Why Multimodality Beats Scale
A 1-billion-parameter model conditioned on RNA chemical-probing reactivity folds a held-out transcript to an F1 of 0.987 against an experimentally guided reference.
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#splicing
2 articles tagged with #splicing.
How AlphaGenome Models Gene Regulation: 2D Embeddings, Splicing, and the Race to Read Non-Coding DNA
A technical look at AlphaGenome's architecture, its 2D pairwise embeddings for splicing prediction, and what the model means for clinical variant interpretation.