A Bioinformatician's Guide to Choosing Genomic Foundation Models
•21 min read
#foundation models#genomics#bioinformatics#deep learning#protein language models#dna models#esm-2#dnabert-2#hyenadna#scgpt
A practical guide to selecting genomic foundation models for bioinformatics tasks. Covers ESM-2, DNABERT-2, HyenaDNA, Nucleotide Transformer, scGPT, and Evo with specific recommendations for DNA sequence analysis, protein structure prediction, and single-cell analysis based on hardware requirements, inference speed, and task type.